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Development of biodegradable polymer based tamoxifen citrate loaded nanoparticles and effect of some manufacturing process parameters on them: a physicochemical and in-vitro evaluation

The aim of the present study was to develop nanoparticles of tamoxifen citrate, a non-steroidal antiestrogenic drug used for the treatment of breast cancer. Biodegradable poly (D, L- lactide-co-glycolide)-85:15 (PLGA) was used to develop nanoparticles of tamoxifen citrate by multiple emulsification...

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Autors principals: Sahana, Basudev, Santra, Kousik, Basu, Sumit, Mukherjee, Biswajit
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939707/
https://ncbi.nlm.nih.gov/pubmed/20856837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S9962
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