Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

Efficient vaccination against infectious agents and tumors depends on specific antigen targeting to dendritic cells (DCs). We report here that biosafe coronavirus-based vaccine vectors facilitate delivery of multiple antigens and immunostimulatory cytokines to professional antigen-presenting cells i...

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Main Authors: Cervantes-Barragan, Luisa, Züst, Roland, Maier, Reinhard, Sierro, Sophie, Janda, Jozef, Levy, Frederic, Speiser, Daniel, Romero, Pedro, Rohrlich, Pierre-Simon, Ludewig, Burkhard, Thiel, Volker
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Microbiology 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939679/
https://ncbi.nlm.nih.gov/pubmed/20844609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00171-10
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