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Bradykinin Decreases Podocyte Permeability through ADAM17-Dependent Epidermal Growth Factor Receptor Activation and Zonula Occludens-1 Rearrangement

Recent data show that increases in bradykinin (BK) concentration contribute to the beneficial effects of angiotensin-converting enzyme inhibitor (ACEI) treatment in chronic kidney disease. However, the possible role of BK in attenuated proteinuria, often seen in ACEI-treated patients, is not well st...

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Detalhes bibliográficos
Main Authors: Dey, Mamon, Baldys, Aleksander, Sumter, Dezmond B., Göőz, Pal, Luttrell, Louis M., Raymond, John R., Göőz, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939663/
https://ncbi.nlm.nih.gov/pubmed/20566668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.168054
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