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Gene expression profiling in brain of mice exposed to the marine neurotoxin ciguatoxin reveals an acute anti-inflammatory, neuroprotective response

BACKGROUND: Ciguatoxins (CTXs) are polyether marine neurotoxins and potent activators of voltage-gated sodium channels. This toxin is carried by multiple reef-fish species and human consumption of ciguatoxins can result in an explosive gastrointestinal/neurologic illness. This study characterizes th...

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Detalhes bibliográficos
Main Authors: Ryan, James C, Morey, Jeanine S, Bottein, Marie-Yasmine Dechraoui, Ramsdell, John S, Van Dolah, Frances M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939656/
https://ncbi.nlm.nih.gov/pubmed/20796285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-107
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