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A haplotype inference algorithm for trios based on deterministic sampling

BACKGROUND: In genome-wide association studies, thousands of individuals are genotyped in hundreds of thousands of single nucleotide polymorphisms (SNPs). Statistical power can be increased when haplotypes, rather than three-valued genotypes, are used in analysis, so the problem of haplotype phase i...

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Main Authors: Iliadis, Alexandros, Watkinson, John, Anastassiou, Dimitris, Wang, Xiaodong
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939632/
https://ncbi.nlm.nih.gov/pubmed/20727218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-11-78
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