Basic Mechanisms of Arsenic Trioxide (ATO)-Induced Apoptosis in Human Leukemia (HL-60) Cells

BACKGROUND: Acute promyelocytic leukemia (APL) is a blood cancer that affects people of all ages and strikes about 1,500 patients in the United States each year. The standard treatment of APL has been based on the combined administration of all-trans retinoic acid and chemotherapy including anthracy...

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Bibliographic Details
Main Authors: Yedjou, Clement, Tchounwou, Paul, Jenkins, John, McMurray, Robert
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939535/
https://ncbi.nlm.nih.gov/pubmed/20796291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-3-28
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