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ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

The conserved TREX mRNA export complex is known to contain UAP56, Aly, Tex1, and the THO complex. Here, we carried out proteomic analysis of immunopurified human TREX complex and identified the protein CIP29 as the only new component with a clear yeast relative (known as Tho1). Tho1 is known to func...

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Detalles Bibliográficos
Main Authors: Dufu, Kobina, Livingstone, Michaela J., Seebacher, Jan, Gygi, Steven P., Wilson, Stuart A., Reed, Robin
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939366/
https://ncbi.nlm.nih.gov/pubmed/20844015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1898610
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