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T-Cell Dysfunction and Inhibitory Receptors in Hepatitis C Virus Infection

Dysfunction of the virus-specific T cells is a cardinal feature in chronic persistent viral infections such as one caused by hepatitis C virus (HCV). In chronic HCV infection, virus-specific dysfunctional CD8 T cells often overexpress various inhibitory receptors. Programmed cell death 1 (PD-1) was...

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Bibliographic Details
Main Authors: Lee, Jino, Suh, William I., Shin, Eui-Cheol
Format: Artigo
Language:Inglês
Published: The Korean Association of Immunologists 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939356/
https://ncbi.nlm.nih.gov/pubmed/20844736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2010.10.4.120
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