Alpha 4-integrins mediate antigen-induced late bronchial responses and prolonged airway hyperresponsiveness in sheep.

Eosinophils and T lymphocytes are thought to be involved in allergic airway inflammation. Both cells express the alpha 4 beta 1-integrin, very late antigen-4 (VLA-4, CD49d/CD29); alpha 4-integrins can promote cellular adhesion and activation. Therefore, we examined the in vivo effects of a blocking...

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Main Authors: Abraham, W M, Sielczak, M W, Ahmed, A, Cortes, A, Lauredo, I T, Kim, J, Pepinsky, B, Benjamin, C D, Leone, D R, Lobb, R R
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC293928/
https://ncbi.nlm.nih.gov/pubmed/8113411
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