Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.

The loss of T helper cell (TH) function in asymptomatic HIV type 1-infected individuals occurs before the decline in CD4+ T cells. At least part of the loss in TH function results from changes in immunoregulatory cytokine profiles. To investigate the role of IL-10 in such dysregulation, we tested wh...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Clerici, M, Wynn, T A, Berzofsky, J A, Blatt, S P, Hendrix, C W, Sher, A, Coffman, R L, Shearer, G M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293925/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113410/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117031
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