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Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus.

The loss of T helper cell (TH) function in asymptomatic HIV type 1-infected individuals occurs before the decline in CD4+ T cells. At least part of the loss in TH function results from changes in immunoregulatory cytokine profiles. To investigate the role of IL-10 in such dysregulation, we tested wh...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Principais autores: Clerici, M, Wynn, T A, Berzofsky, J A, Blatt, S P, Hendrix, C W, Sher, A, Coffman, R L, Shearer, G M
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113410/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117031
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