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ANALYSIS OF THE FUNCTION OF CYTOPLASMIC FIBERS FORMED BY THE RUBELLA VIRUS NONSTRUCTURAL REPLICASE PROTEINS

The P150 and P90 replicase proteins of rubella virus (RUBV), a plus-strand RNA Togavirus, produce a unique cytoplasmic fiber network resembling microtubules. Pharmacological and mutagenic approaches were used to determine if these fibers functioned in virus replication. The pharmacological approach...

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Detalhes bibliográficos
Main Authors: Matthews, Jason D., Tzeng, Wen-Pin, Frey, Teryl K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939240/
https://ncbi.nlm.nih.gov/pubmed/20696450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.07.025
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