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Perforin-secreting killer cell infiltration and expression of a 65-kD heat-shock protein in aortic tissue of patients with Takayasu's arteritis.

Cell-mediated autoimmunity has been strongly implicated in the pathogenesis of vascular cell injury in Takayasu's arteritis. To clarify the immunological mechanisms involved, we examined the expression of a cytolytic factor, perforin in infiltrating cells of aortic tissue samples from seven pat...

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Detalhes bibliográficos
Main Authors: Seko, Y, Minota, S, Kawasaki, A, Shinkai, Y, Maeda, K, Yagita, H, Okumura, K, Sato, O, Takagi, A, Tada, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC293919/
https://ncbi.nlm.nih.gov/pubmed/7906697
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