Role of CD45 Signaling Pathway in Galactoxylomannan-Induced T Cell Damage

Previously, we reported that Galactoxylomannan (GalXM) activates the extrinsic and intrinsic apoptotic pathways through an interaction with the glycoreceptors on T cells. In this study we establish the role of the glycoreceptor CD45 in GalXM-induced T cell apoptosis, using CD45(+/+) and CD45(−/−) ce...

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Main Authors: Pericolini, Eva, Gabrielli, Elena, Bistoni, Giovanni, Cenci, Elio, Perito, Stefano, Chow, Siu-Kei, Riuzzi, Francesca, Donato, Rosario, Casadevall, Arturo, Vecchiarelli, Anna
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2010
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939064/
https://ncbi.nlm.nih.gov/pubmed/20856869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012720
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