Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men

BACKGROUND: The APOE ε4 allele is an established risk factor for Alzheimer disease (AD), yet findings are mixed for how early its effects are manifest. One reason for the mixed results could be the presence of interaction effects with other AD risk factors. Increasing evidence indicates that testost...

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Autors principals: Panizzon, M.S., Hauger, R., Dale, A.M., Eaves, L.J., Eyler, L.T., Fischl, B., Fennema-Notestine, C., Franz, C.E., Grant, M.D., Jak, A.J., Jacobson, K.C., Lyons, M.J., Mendoza, S.P., Neale, M.C., Prom-Wormley, E.C., Seidman, L.J., Tsuang, M.T., Xian, H., Kremen, W.S.
Format: Artigo
Idioma:Inglês
Publicat: American Academy of Neurology 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938973/
https://ncbi.nlm.nih.gov/pubmed/20819998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181f11deb
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