MRS in presymptomatic MAPT mutation carriers: A potential biomarker for tau-mediated pathology

OBJECTIVE: To determine the proton magnetic resonance spectroscopy ((1)H MRS) changes in carriers of microtubule-associated protein (MAPT) mutations in a case-control study. METHODS: Patients with MAPT mutations (N279K, V337M, R406W, IVS9-10G>T, P301L) from 5 different families (n = 24) underwent...

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Autors principals: Kantarci, K., Boeve, B.F., Wszolek, Z.K., Rademakers, R., Whitwell, J.L., Baker, M.C., Senjem, M.L., Samikoglu, A.R., Knopman, D.S., Petersen, R.C., Jack, C.R.
Format: Artigo
Idioma:Inglês
Publicat: American Academy of Neurology 2010
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938968/
https://ncbi.nlm.nih.gov/pubmed/20805522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3181f073c7
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