Efficacy and safety of different doses and retreatment of rituximab: a randomised, placebo-controlled trial in patients who are biological naïve with active rheumatoid arthritis and an inadequate response to methotrexate (Study Evaluating Rituximab's Efficacy in MTX iNadequate rEsponders (SERENE))

OBJECTIVES: This phase III study evaluated the efficacy and safety of rituximab plus methotrexate (MTX) in patients with active rheumatoid arthritis (RA) who had an inadequate response to MTX and who were naïve to prior biological treatment. METHODS: Patients with active disease on stable MTX (10–25...

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Detalhes bibliográficos
Main Authors: Emery, P, Deodhar, A, Rigby, W F, Isaacs, J D, Combe, B, Racewicz, A J, Latinis, K, Abud-Mendoza, C, Szczepański, L J, Roschmann, R A, Chen, A, Armstrong, G K, Douglass, W, Tyrrell, H
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Group 2010
Assuntos:
Clinical and Epidemiological Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938895/
https://ncbi.nlm.nih.gov/pubmed/20488885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/ard.2009.119933
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