PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive T cells

Prostaglandin E(2) (PGE(2)) is an inflammatory mediator often used to increase CCR7 expression in the dendritic cells (DCs) used as cancer vaccines and to enhance their responsiveness to lymph node–associated chemokines. Here, we show that high surface expression of CCR7 on PGE(2)-matured DCs is ass...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Muthuswamy, Ravikumar, Mueller-Berghaus, Jan, Haberkorn, Uwe, Reinhart, Todd A., Schadendorf, Dirk, Kalinski, Pawel
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2010
נושאים:
Immunobiology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938836/
https://ncbi.nlm.nih.gov/pubmed/20498301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-258038
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים