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PGE(2) transiently enhances DC expression of CCR7 but inhibits the ability of DCs to produce CCL19 and attract naive T cells
Prostaglandin E(2) (PGE(2)) is an inflammatory mediator often used to increase CCR7 expression in the dendritic cells (DCs) used as cancer vaccines and to enhance their responsiveness to lymph node–associated chemokines. Here, we show that high surface expression of CCR7 on PGE(2)-matured DCs is ass...
সংরক্ষণ করুন:
| প্রধান লেখক: | , , , , , |
|---|---|
| বিন্যাস: | Artigo |
| ভাষা: | Inglês |
| প্রকাশিত: |
American Society of Hematology
2010
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938836/ https://ncbi.nlm.nih.gov/pubmed/20498301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-258038 |
| ট্যাগগুলো: |
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