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How Can Hydrophobic Association Be Enthalpy Driven?

Hydrophobic association is often recognized as being driven by favorable entropic contributions. Here, using explicit solvent molecular dynamics simulations we investigate binding in a model hydrophobic receptor−ligand system which appears, instead, to be driven by enthalpy and opposed by entropy. W...

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Sonraí Bibleagrafaíochta
Main Authors: Setny, Piotr, Baron, Riccardo, McCammon, J. Andrew
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Chemical Society 2010
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938831/
https://ncbi.nlm.nih.gov/pubmed/20844599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct1003077
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