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The PI-PLC inhibitor U-73122 is a potent inhibitor of the SERCA pump in smooth muscle

In this issue MacMillan and McCarron in 2010 demonstrated that the phospholipase C (PLC) inhibitor U-73122 can potently inhibit Ca(2+) release from isolated smooth muscle cells independent of its effect on PLC. Their data suggest that the PLC inhibitor can block the sarcoplasmic/endoplasmic reticulu...

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Autors principals: Hollywood, MA, Sergeant, GP, Thornbury, KD, McHale, NG
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938801/
https://ncbi.nlm.nih.gov/pubmed/20590620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00795.x
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