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Expression of Actin-interacting Protein 1 Suppresses Impaired Chemotaxis of Dictyostelium Cells Lacking the Na(+)-H(+) Exchanger NHE1

Increased intracellular pH is an evolutionarily conserved signal necessary for directed cell migration. We reported previously that in Dictyostelium cells lacking H(+) efflux by a Na(+)-H(+) exchanger (NHE; Ddnhe1(−)), chemotaxis is impaired and the assembly of filamentous actin (F-actin) is attenua...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Chang-Hoon, Patel, Hitesh, Barber, Diane L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938382/
https://ncbi.nlm.nih.gov/pubmed/20668166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-12-1058
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