Low CD10 mRNA Expression Identifies High-Risk Ductal Carcinoma In Situ (DCIS)

PURPOSE: Optimal management of breast ductal carcinoma in situ (DCIS) is controversial, and many patients are still overtreated. The local death of myoepithelial cells (MECs) is believed to be a pre-requisite to tumor invasion. We thus hypothesized that loss of CD10 expression, a MEC surface peptida...

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Main Authors: Toussaint, Jérôme, Durbecq, Virginie, Altintas, Sevilay, Doriath, Valérie, Rouas, Ghizlane, Paesmans, Marianne, Bedard, Philippe, Haibe-Kains, Benjamin, Tjalma, Wiebren A., Larsimont, Denis, Piccart, Martine, Sotiriou, Christos
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938371/
https://ncbi.nlm.nih.gov/pubmed/20856894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012100
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