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Acetylation of core histones in response to HDAC inhibitors is diminished in mitotic HeLa cells
Histone acetylation is a key modification that regulates chromatin accessibility. Here we show that treatment with butyrate or other histone deacetylase (HDAC) inhibitors does not induce histone hyperacetylation in metaphase-arrested HeLa cells. When compared to similarly treated interphase cells, a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2938188/ https://ncbi.nlm.nih.gov/pubmed/20452346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2010.05.003 |
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