Fusions of Dendritic Cells with Breast Carcinoma Stimulate the Expansion of Regulatory T Cells while Concomitant Exposure to IL-12, CpG Oligodeoxynucleotides, and Anti-CD3/CD28 Promotes the Expansion of Activated Tumor Reactive Cells

Vaccination of patients with dendritic cell (DC)/breast carcinoma fusions stimulated antitumor immune responses in a majority of patients with metastatic disease but only a subset demonstrate evidence of tumor regression. To define the factors that limit vaccine efficacy, we examined the biological...

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Main Authors: Vasir, Baldev, Wu, Zekui, Crawford, Keith, Rosenblatt, Jacalyn, Zarwan, Corrine, Bissonnette, Adam, Kufe, Donald, Avigan, David
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938172/
https://ncbi.nlm.nih.gov/pubmed/18566447
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