Down syndrome childhood acute lymphoblastic leukemia has a unique spectrum of sentinel cytogenetic lesions that influences treatment outcome: a report from the Children's Oncology Group

Children with Down syndrome (DS) have an increased risk of acute lymphoblastic leukemia (ALL) and an inferior outcome. We reviewed data from 2811 children with ALL enrolled in Children's Oncology Group P9900, which included prospective testing for the major cytogenetic lesions in childhood ALL:...

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Bibliographic Details
Main Authors: Maloney, Kelly W., Carroll, William L., Carroll, Andrew J., Devidas, Meenakshi, Borowitz, Michael J., Martin, Paul L., Pullen, Jeanette, Whitlock, James A., Willman, Cheryl L., Winick, Naomi J., Camitta, Bruce M., Hunger, Stephen P.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2010
Subjects:
Clinical Trials and Observations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2938126/
https://ncbi.nlm.nih.gov/pubmed/20442364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235291
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