Insight into Invertebrate Defensin Mechanism of Action: OYSTER DEFENSINS INHIBIT PEPTIDOGLYCAN BIOSYNTHESIS BY BINDING TO LIPID II

Three oyster defensin variants (Cg-Defh1, Cg-Defh2, and Cg-Defm) were produced as recombinant peptides and characterized in terms of activities and mechanism of action. In agreement with their spectrum of activity almost specifically directed against Gram-positive bacteria, oyster defensins were sho...

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Bibliographische Detailangaben
Hauptverfasser: Schmitt, Paulina, Wilmes, Miriam, Pugnière, Martine, Aumelas, André, Bachère, Evelyne, Sahl, Hans-Georg, Schneider, Tanja, Destoumieux-Garzón, Delphine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937951/
https://ncbi.nlm.nih.gov/pubmed/20605792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.143388
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