T-LAK Cell-originated Protein Kinase (TOPK) Phosphorylation of Prx1 at Ser-32 Prevents UVB-induced Apoptosis in RPMI7951 Melanoma Cells through the Regulation of Prx1 Peroxidase Activity

Protein kinases are potential targets for the prevention and control of UV-induced skin cancer. T-cell-originated protein kinase (TOPK) is highly expressed in skin cancer cells, but its specific function is still unknown. We investigated the role of TOPK in UVB-induced apoptosis in RPMI7951 human me...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Zykova, Tatyana A., Zhu, Feng, Vakorina, Tatyana I., Zhang, Jishuai, Higgins, Lee Ann, Urusova, Darya V., Bode, Ann M., Dong, Zigang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937944/
https://ncbi.nlm.nih.gov/pubmed/20647304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.135905
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares