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Post-transcriptional Mechanisms Contribute to the Suppression of the ErbB3 Negative Regulator Protein Nrdp1 in Mammary Tumors

The ErbB2 and ErbB3 receptor tyrosine kinases act synergistically to promote cellular properties associated with tumor development. Previous studies indicate that endogenous ErbB3 protein is markedly elevated in mouse mammary tumors induced by transgenic ErbB2 overexpression. However, this occurs in...

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Bibliografiske detaljer
Main Authors: Ingalla, Ellen Q., Miller, Jamie K., Wald, Jessica H., Workman, Heather C., Kaur, Rouminder P., Yen, Lily, Fry, William H. D., Borowsky, Alexander D., Young, Lawrence J. T., Sweeney, Colleen, Carraway, Kermit L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937896/
https://ncbi.nlm.nih.gov/pubmed/20628057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127977
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