Long-Lasting Protective Antiviral Immunity Induced by Passive Immunotherapies Requires both Neutralizing and Effector Functions of the Administered Monoclonal Antibody

Using FrCas(E) retrovirus-infected newborn mice as a model system, we have shown recently that a long-lasting antiviral immune response essential for healthy survival emerges after a short treatment with a neutralizing (667) IgG2a isotype monoclonal antibody (MAb). This suggested that the mobilizati...

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Detalhes bibliográficos
Main Authors: Nasser, Roudaina, Pelegrin, Mireia, Michaud, Henri-Alexandre, Plays, Marc, Piechaczyk, Marc, Gros, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937798/
https://ncbi.nlm.nih.gov/pubmed/20610721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00568-10
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