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Induction of angiotensin converting enzyme in the neointima after vascular injury. Possible role in restenosis.

Angiotensin II (Ang II) promotes growth of vascular smooth muscle cells in vitro. Consistent with this, Ang II enhances neointimal proliferation in vivo after vascular injury, while angiotensin converting enzyme (ACE) inhibitors attenuate this process. Since tissue ACE plays a key role in the contro...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Rakugi, H, Kim, D K, Krieger, J E, Wang, D S, Dzau, V J, Pratt, R E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1994
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC293775/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8282805/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116965
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