Prophylactic Treatment with a G Glycoprotein Monoclonal Antibody Reduces Pulmonary Inflammation in Respiratory Syncytial Virus (RSV)-Challenged Naïve and Formalin-Inactivated RSV-Immunized BALB/c Mice

We examined whether prophylactically administered anti-respiratory syncytial virus (anti-RSV) G monoclonal antibody (MAb) would decrease the pulmonary inflammation associated with primary RSV infection and formalin-inactivated RSV (FI-RSV)-enhanced disease in mice. MAb 131-2G administration 1 day pr...

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Detalhes bibliográficos
Main Authors: Radu, Gertrud U., Caidi, Hayat, Miao, Congrong, Tripp, Ralph A., Anderson, Larry J., Haynes, Lia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937657/
https://ncbi.nlm.nih.gov/pubmed/20592094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00451-10
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