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Expression of MIP-1α (CCL3) by a Recombinant Rabies Virus Enhances Its Immunogenicity by Inducing Innate Immunity and Recruiting Dendritic Cells and B Cells

Previously, we showed that overexpression of MIP-1α in mouse brain further decreased rabies virus (RABV) pathogenicity (L. Zhao, H. Toriumi, Y. Kuang, H. Chen, and Z. F. Fu, J. Virol., 83:11808-11818, 2009). In the present study, the immunogenicity of recombinant RABV expressing MIP-1α (rHEP-MIP1α)...

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Detalhes bibliográficos
Main Authors: Zhao, Ling, Toriumi, Harufusa, Wang, Hualei, Kuang, Yi, Guo, Xiaofeng, Morimoto, Kinjiro, Fu, Zhen F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937656/
https://ncbi.nlm.nih.gov/pubmed/20592092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00326-10
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