The Clinically Approved Proteasome Inhibitor PS-341 Efficiently Blocks Influenza A Virus and Vesicular Stomatitis Virus Propagation by Establishing an Antiviral State

Recently it has been shown that the proinflammatory NF-κB pathway promotes efficient influenza virus propagation. Based on these findings, it was suggested that NF-κB blockade may be a promising approach for antiviral intervention. The classical virus-induced activation of the NF-κB pathway requires...

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Bibliografiska uppgifter
Huvudupphovsmän: Dudek, Sabine Eva, Luig, Christina, Pauli, Eva-Katharina, Schubert, Ulrich, Ludwig, Stephan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2010
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937650/
https://ncbi.nlm.nih.gov/pubmed/20592098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00533-10
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