Nonintegrating Foamy Virus Vectors

Foamy viruses (FVs), or spumaviruses, are integrating retroviruses that have been developed as vectors. Here we generated nonintegrating foamy virus (NIFV) vectors by introducing point mutations into the highly conserved DD35E catalytic core motif of the foamy virus integrase sequence. NIFV vectors...

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Bibliografske podrobnosti
Main Authors: Deyle, David R., Li, Yi, Olson, Erik M., Russell, David W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Gene Delivery
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937610/
https://ncbi.nlm.nih.gov/pubmed/20592072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00394-10
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