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Modulating Expression of Peripherin/rds in Transgenic Mice: Critical Levels and the Effect of Overexpression

PURPOSE: Mutations in the photoreceptor-specific protein peripherin/rds are associated with multiple retinal diseases. To date, attempts to achieve complete structural and functional rescue in animal models of peripherin/rds-induced retinal degeneration have not been successful. Gene therapy – direc...

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Detalhes bibliográficos
Main Authors: Nour, May, Ding, Xi-Qin, Stricker, Heidi, Fliesler, Steven J., Naash, Muna I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937570/
https://ncbi.nlm.nih.gov/pubmed/15277471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.04-0065
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