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Protein Tyrosine Kinase 6 Directly Phosphorylates AKT and Promotes AKT Activation in Response to Epidermal Growth Factor

Protein tyrosine kinase 6 (PTK6) is a nonmyristoylated Src-related intracellular tyrosine kinase. Although not expressed in the normal mammary gland, PTK6 is expressed in a majority of human breast tumors examined, and it has been linked to ErbB receptor signaling and AKT activation. Here we demonst...

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Autors principals: Zheng, Yu, Peng, Maoyu, Wang, Zebin, Asara, John M., Tyner, Angela L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937549/
https://ncbi.nlm.nih.gov/pubmed/20606012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00024-10
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