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The Embryonic Transcription Cofactor LBH Is a Direct Target of the Wnt Signaling Pathway in Epithelial Development and in Aggressive Basal Subtype Breast Cancers

Limb-bud and heart (LBH) is a novel key transcriptional regulator of vertebrate development. However, the molecular mechanisms upstream of LBH and its role in adult development are unknown. Here we show that in epithelial development, LBH expression is tightly controlled by Wnt signaling. LBH is tra...

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Auteurs principaux: Rieger, Megan E., Sims, Andrew H., Coats, Ebony R., Clarke, Robert B., Briegel, Karoline J.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2010
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937547/
https://ncbi.nlm.nih.gov/pubmed/20606007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01418-09
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