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Accidental Selection and Intentional Restoration of Sporulation-Deficient Bacillus anthracis Mutants

We demonstrate the frequent accidental enrichment of spontaneous sporulation-deficient mutants of Bacillus anthracis on solid medium and identify contributing factors. Mutations in spo0A, encoding the master regulator of sporulation initiation, were found in 38 of 53 mutants. Transductions using bac...

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Autori principali: Sastalla, Inka, Rosovitz, M. J., Leppla, Stephen H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937495/
https://ncbi.nlm.nih.gov/pubmed/20639373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00950-10
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