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Immunomodulatory Effects of Serotype B Glucuronoxylomannan from Cryptococcus gattii Correlate with Polysaccharide Diameter

Glucuronoxylomannan (GXM), the major capsular component in the Cryptococcus complex, interacts with the immune system in multiple ways, which include the activation of Toll-like receptors (TLRs) and the modulation of nitric oxide (NO) production by phagocytes. In this study, we analyzed several stru...

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Bibliographic Details
Main Authors: Fonseca, Fernanda L., Nohara, Lilian L., Cordero, Radames J. B., Frases, Susana, Casadevall, Arturo, Almeida, Igor C., Nimrichter, Leonardo, Rodrigues, Marcio L.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937472/
https://ncbi.nlm.nih.gov/pubmed/20547742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00111-10
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