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Leishmania donovani Amastigotes Impair Gamma Interferon-Induced STAT1α Nuclear Translocation by Blocking the Interaction between STAT1α and Importin-α5

The protozoan parasite Leishmania donovani, the etiological agent of visceral leishmaniasis, is renowned for its capacity to sabotage macrophage functions and signaling pathways stimulated by activators such as gamma interferon (IFN-γ). Our knowledge of the strategies utilized by L. donovani to impa...

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Detalhes bibliográficos
Main Authors: Matte, Christine, Descoteaux, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937469/
https://ncbi.nlm.nih.gov/pubmed/20566692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00046-10
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