A Porphyromonas gingivalis Mutant Defective in a Putative Glycosyltransferase Exhibits Defective Biosynthesis of the Polysaccharide Portions of Lipopolysaccharide, Decreased Gingipain Activities, Strong Autoaggregation, and Increased Biofilm Formation

The Gram-negative anaerobic bacterium Porphyromonas gingivalis is a major pathogen in periodontal disease, one of the biofilm-caused infectious diseases. The bacterium possesses potential virulence factors, including fimbriae, proteinases, hemagglutinin, lipopolysaccharide (LPS), and outer membrane...

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Autori principali: Yamaguchi, Mikiyo, Sato, Keiko, Yukitake, Hideharu, Noiri, Yuichiro, Ebisu, Shigeyuki, Nakayama, Koji
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
Soggetti:
Molecular Pathogenesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937442/
https://ncbi.nlm.nih.gov/pubmed/20624909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00071-10
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