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Systems-Level Metabolic Flux Profiling Elucidates a Complete, Bifurcated Tricarboxylic Acid Cycle in Clostridium acetobutylicum

Obligatory anaerobic bacteria are major contributors to the overall metabolism of soil and the human gut. The metabolic pathways of these bacteria remain, however, poorly understood. Using isotope tracers, mass spectrometry, and quantitative flux modeling, here we directly map the metabolic pathways...

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Autori principali: Amador-Noguez, Daniel, Feng, Xiao-Jiang, Fan, Jing, Roquet, Nathaniel, Rabitz, Herschel, Rabinowitz, Joshua D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937365/
https://ncbi.nlm.nih.gov/pubmed/20622067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00490-10
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