Cerebrospinal T-Cell Responses Aid in the Diagnosis of Tuberculous Meningitis in a Human Immunodeficiency Virus– and Tuberculosis-Endemic Population

Rationale: Current tools for the rapid diagnosis of tuberculous meningitis (TBM) are suboptimal. We evaluated the clinical utility of a quantitative RD-1 IFN-γ T-cell enzyme-linked immunospot (ELISPOT) assay (T-SPOT.TB), using cerebrospinal fluid cells for the rapid immunodiagnosis of TBM. Objective...

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Autors principals: Patel, Vinod B., Singh, Ravesh, Connolly, Cathy, Coovadia, Yacoob, Peer, Abdool K. C., Parag, Priyashini, Kasprowicz, Victoria, Zumla, Alimuddin, Ndung'u, Thumbi, Dheda, Keertan
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2010
Matèries:
I. Tuberculosis and Mycobacterial Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937246/
https://ncbi.nlm.nih.gov/pubmed/20442433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200912-1931OC
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