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Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice

Adipocyte complement-related protein (30 kDa) (Acrp30), a secreted protein of unknown function, is exclusively expressed in differentiated adipocytes; its mRNA is decreased in obese humans and mice. Here we describe novel pharmacological properties of the protease-generated globular head domain of A...

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Main Authors: Fruebis, Joachim, Tsao, Tsu-Shuen, Javorschi, Sandrine, Ebbets-Reed, Dana, Erickson, Mary Ruth S., Yen, Frances T., Bihain, Bernard E., Lodish, Harvey F.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC29372/
https://ncbi.nlm.nih.gov/pubmed/11172066
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