uPAR and/or MMP-9 inhibition induces apoptosis signaling through lipid rafts in glioblastoma xenograft cells

siRNA mediated transcriptional knockdown of urokinase plasminogen activator receptor (uPAR) and matrix metalloproteinase-9 (MMP-9), alone or in combination, inhibits uPAR and/or MMP-9 expression and induces apoptosis in the human glioblastoma xenograft cell lines 4910 and 5310. siRNA against uPAR (p...

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Bibliografiska uppgifter
Huvudupphovsmän: Chetty, Chandramu, Lakka, Sajani S., Bhoopathi, Praveen, Gondi, Christopher S., Veeravalli, Krishna K., Fassett, Daniel, Klopfenstein, Jeffrey D., Dinh, Dzung H., Gujrati, Meena, Rao, Jasti S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937072/
https://ncbi.nlm.nih.gov/pubmed/20716639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-10-0245
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