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TYPE I INTERFERON SIGNALS CONTROL THEILER’S VIRUS INFECTION SITE, CELLULAR INFILTRATION AND T CELL STIMULATION IN THE CNS

Theiler’s murine encephalomyelitis virus (TMEV) establishes a persistent infection in the central nervous system (CNS). To examine the role of type I interferon (IFN-I)-mediated signals in TMEV infection, mice lacking a subunit of the type I IFN receptor (IFN-IR KO mice) were utilized. In contrast t...

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Detalhes bibliográficos
Main Authors: Jin, Young-Hee, Hou, Wanqiu, Kim, Seung Jae, Fuller, Alyson C., Kang, Bongsu, Goings, Gwen, Miller, Stephen D., Kim, Byung S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2937062/
https://ncbi.nlm.nih.gov/pubmed/20538350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2010.05.028
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