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Structure and cellular roles of the RMI core complex from the Bloom syndrome dissolvasome
BLM, the protein product of the gene mutated in Bloom syndrome, is one of five human RecQ helicases. It functions to separate double Holliday junction DNA without genetic exchange as a component of the “dissolvasome”, which also includes topoisomerase IIIα and the RMI (RecQ-mediated genome instabili...
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Main Authors: | , , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2937010/ https://ncbi.nlm.nih.gov/pubmed/20826341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.06.009 |
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