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Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure

Impaired insulin signaling via phosphatidylinositol 3-kinase/Akt to endothelial nitric oxide synthase (eNOS) in the vasculature has been postulated to lead to arterial dysfunction and hypertension in obesity and other insulin resistant states. To investigate this, we compared insulin signaling in th...

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書誌詳細
主要な著者: Symons, J. David, McMillin, Shawna L., Riehle, Christian, Tanner, Jason, Palionyte, Milda, Hillas, Elaine, Jones, Deborah, Cooksey, Robert C., Birnbaum, Morris J., McClain, Donald A., Zhang, Quan-Jiang, Gale, Derrick, Wilson, Lloyd J., Abel, E. Dale
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936913/
https://ncbi.nlm.nih.gov/pubmed/19342603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.189316
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