Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure

Impaired insulin signaling via phosphatidylinositol 3-kinase/Akt to endothelial nitric oxide synthase (eNOS) in the vasculature has been postulated to lead to arterial dysfunction and hypertension in obesity and other insulin resistant states. To investigate this, we compared insulin signaling in th...

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Autores principales: Symons, J. David, McMillin, Shawna L., Riehle, Christian, Tanner, Jason, Palionyte, Milda, Hillas, Elaine, Jones, Deborah, Cooksey, Robert C., Birnbaum, Morris J., McClain, Donald A., Zhang, Quan-Jiang, Gale, Derrick, Wilson, Lloyd J., Abel, E. Dale
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936913/
https://ncbi.nlm.nih.gov/pubmed/19342603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.189316
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