Spinal glial TLR4-mediated nociception and production of prostaglandin E(2) and TNF

BACKGROUND AND PURPOSE: Toll-like receptor 4 (TLR4) expressed on spinal microglia and astrocytes has been suggested to play an important role in the regulation of pain signalling. The purpose of the present work was to examine the links between TLR4, glial activation and spinal release of prostaglan...

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Detalhes bibliográficos
Main Authors: Saito, O, Svensson, CI, Buczynski, MW, Wegner, K, Hua, X-Y, Codeluppi, S, Schaloske, RH, Deems, RA, Dennis, EA, Yaksh, TL
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936846/
https://ncbi.nlm.nih.gov/pubmed/20649577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00811.x
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