Investigation of the distribution and function of α-adrenoceptors in the sheep isolated internal anal sphincter

BACKGROUND AND PURPOSE: We have investigated the distribution of α-adrenoceptors in sheep internal anal sphincter (IAS), as a model for the human tissue, and evaluated various imidazoline derivatives for potential treatment of faecal incontinence. EXPERIMENTAL APPROACH: Saturation and competition bi...

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Detalhes bibliográficos
Main Authors: Rayment, SJ, Eames, T, Simpson, JAD, Dashwood, MR, Henry, Y, Gruss, H, Acheson, AG, Scholefield, JH, Wilson, VG
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936844/
https://ncbi.nlm.nih.gov/pubmed/20649575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00842.x
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