High concentrations of dexmedetomidine inhibit compound action potentials in frog sciatic nerves without α(2) adrenoceptor activation

BACKGROUND AND PURPOSE: Dexmedetomidine, an α(2)-adrenoceptor agonist, exhibits anti-nociceptive actions at the spinal cord and enhances the effect of local anaesthetics in the peripheral nervous system. Although the latter action may be attributed in part to inhibition of nerve conduction produced...

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Main Authors: Kosugi, Toshifumi, Mizuta, Kotaro, Fujita, Tsugumi, Nakashima, Mikio, Kumamoto, Eiichi
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936839/
https://ncbi.nlm.nih.gov/pubmed/20649570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00833.x
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